BDBM249900 US10005782, Compound 27b::US9447106, 27::US9556188, Compound 27

SMILES NC(=O)c1c2NCCC(C3CCN(CC3)C(=O)C=C)n2nc1-c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=RNOAOAWBMHREKO-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 249900   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM249900(US10005782, Compound 27b | US9447106, 27 | US95561...)
Affinity DataIC50:  1nMAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM249900(US10005782, Compound 27b | US9447106, 27 | US95561...)
Affinity DataIC50:  0.330nMAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM249900(US10005782, Compound 27b | US9447106, 27 | US95561...)
Affinity DataIC50:  2nMAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
In DepthDetails US Patent