BDBM24997 4-[7-(3-aminopropoxy)-1-ethyl-4-phenyl-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine::D3RKN_37::oxadiazole-containing compound, 10

SMILES CCn1c(nc2c(ncc(OCCCN)c12)-c1ccccc1)-c1nonc1N

InChI Key InChIKey=OAYXVYXQZWJEBE-UHFFFAOYSA-N

Data  3 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 24997   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM24997(4-[7-(3-aminopropoxy)-1-ethyl-4-phenyl-1H-imidazo[...)
Affinity DataIC50:  331nMpH: 7.5 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM24997(4-[7-(3-aminopropoxy)-1-ethyl-4-phenyl-1H-imidazo[...)
Affinity DataIC50:  1.00E+3nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM24997(4-[7-(3-aminopropoxy)-1-ethyl-4-phenyl-1H-imidazo[...)
Affinity DataKd:  55nMAssay Description:D3R2023More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM24997(4-[7-(3-aminopropoxy)-1-ethyl-4-phenyl-1H-imidazo[...)
Affinity DataKd:  1.40E+3nMAssay Description:D3R2021More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM24997(4-[7-(3-aminopropoxy)-1-ethyl-4-phenyl-1H-imidazo[...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2022More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM24997(4-[7-(3-aminopropoxy)-1-ethyl-4-phenyl-1H-imidazo[...)
Affinity DataIC50:  44nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed