BDBM24999 4-[7-(3-aminopropoxy)-1-ethyl-4-(furan-3-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine::oxadiazole-containing compound, 11b

SMILES CCn1c(nc2c(ncc(OCCCN)c12)-c1ccoc1)-c1nonc1N

InChI Key InChIKey=SXRCGQAHDJRHJC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 24999   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM24999(4-[7-(3-aminopropoxy)-1-ethyl-4-(furan-3-yl)-1H-im...)
Affinity DataIC50:  79nMpH: 7.5 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-1(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM24999(4-[7-(3-aminopropoxy)-1-ethyl-4-(furan-3-yl)-1H-im...)
Affinity DataIC50:  71nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM24999(4-[7-(3-aminopropoxy)-1-ethyl-4-(furan-3-yl)-1H-im...)
Affinity DataIC50:  562nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibosomal protein S6 kinase alpha-5(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM24999(4-[7-(3-aminopropoxy)-1-ethyl-4-(furan-3-yl)-1H-im...)
Affinity DataIC50:  162nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed