BDBM250030 US10005782, Compound 152::US9447106, 152::US9556188, Compound 152

SMILES NC(=O)c1c2NCCC(c3ccccc3NC(=O)C=C)n2nc1-c1ccc(F)c(Br)c1

InChI Key InChIKey=GMVXDNCTYYLQTI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 250030   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM250030(US10005782, Compound 152 | US9447106, 152 | US9556...)
Affinity DataIC50:  1.20nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM250030(US10005782, Compound 152 | US9447106, 152 | US9556...)
Affinity DataIC50:  1.20nMAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM250030(US10005782, Compound 152 | US9447106, 152 | US9556...)
Affinity DataIC50:  1.20nMT: 2°CAssay Description:Compounds disclosed herein were tested for inhibition of Btk kinase activity in an assay based on time-resolved fluorescence resonance energy transfe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent