BDBM250510 US9469639, Compound (IV)

SMILES Cc1cccc(NC(=O)Nc2ccc(-c3cncc4[nH]nc(N)c34)c3ccccc23)c1

InChI Key InChIKey=JCKMPGSSOFUEAB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 250510   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Radiant Pharma & Tech.

US Patent
LigandPNGBDBM250510(US9469639, Compound (IV))
Affinity DataIC50:  6.70nMT: 2°CAssay Description:Experimental Procedures(1) Kinase reaction substrate Poly(Glu, Tyr, 4:1) was diluted to 20 μg/ml with potassium ion-free PBS, and enzyme labeled pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Radiant Pharma & Tech.

US Patent
LigandPNGBDBM250510(US9469639, Compound (IV))
Affinity DataIC50:  4.30nMT: 2°CAssay Description:Experimental Procedures(1) Kinase reaction substrate Poly(Glu, Tyr, 4:1) was diluted to 20 μg/ml with potassium ion-free PBS, and enzyme labeled pla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent