BDBM251922 US10065961, Compound 22::US10683295, Compound 22::US10941151, Compound 22::US9475814, 22

SMILES C[C@H]1N(CCn2c1nnc2-c1nc(C)c(C)s1)C(=O)c1ccc(cc1)-c1cccs1

InChI Key InChIKey=KSIGHAFTVLYICN-CQSZACIVSA-N

Data  4 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 251922   

TargetNeuromedin-K receptor(Homo sapiens (Human))
Ogeda

US Patent
LigandPNGBDBM251922(US10065961, Compound 22 | US10683295, Compound 22 ...)
Affinity DataKi:  21nMAssay Description:The antagonist activity of compounds of the invention is measured following pre-incubation (3 minutes) of the compound with the cells, followed by ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNeuromedin-K receptor(Homo sapiens (Human))
Ogeda

US Patent
LigandPNGBDBM251922(US10065961, Compound 22 | US10683295, Compound 22 ...)
Affinity DataIC50:  21nMAssay Description:The antagonist activity of compounds of the invention is measured following pre-incubation (3 minutes) of the compound with the cells, followed by ad...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTranscriptional regulator ERG(Homo sapiens (Human))
Ogeda

US Patent
LigandPNGBDBM251922(US10065961, Compound 22 | US10683295, Compound 22 ...)
Affinity DataIC50:  1.20E+4nMAssay Description:The human Ether-a-go-go Related Gene (hERG) encodes the inward rectifying voltage gated potassium channel in the heart (IKr) which is involved in car...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent