BDBM254104 US9505739, 100

SMILES Cc1cccc(c1)C1CC(CCN1C(=O)[C@@H]1CNC[C@]11CCCc2nc(Cl)ccc12)c1ccccc1

InChI Key InChIKey=SHGDACKXZZBVAK-RJENHULTSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 254104   

TargetBeta-secretase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM254104(US9505739, 100)
Affinity DataIC50:  450nMpH: 6.5Assay Description:A homogeneous end point electrochemiluminescence (ECL) assay is performed using a biotinylated BACE substrate. The Km of the substrate is approximate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent