BDBM25480 2-(3-fluoro-4-methylphenyl)-4-(4-fluorophenyl)-N-(1H-indazol-5-yl)-6-methyl-1,4-dihydropyrimidine-5-carboxamide::Dihydropyrimidine, 9

SMILES CC1=C(C(NC(=N1)c1ccc(C)c(F)c1)c1ccc(F)cc1)C(=O)Nc1ccc2[nH]ncc2c1

InChI Key InChIKey=AUZZJWUIAZQEBQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25480   

TargetRho-associated protein kinase 1(Homo sapiens (Human))
Gsk

LigandPNGBDBM25480(2-(3-fluoro-4-methylphenyl)-4-(4-fluorophenyl)-N-(...)
Affinity DataIC50:  104nMpH: 7.4 T: 2°CAssay Description:The assay of Rock-1 activity involved incubation with peptide substrate and ATP33, and the incorporation of P33 into the peptide was quantified by Sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed