BDBM255493 US10828301, Compound R940269::US9499493, R940269

SMILES Cc1cc(Nc2nc(Nc3cccc(OCCN4CCOCC4)c3)ncc2F)cc(Cl)c1O

InChI Key InChIKey=IDLAZIMFGWINNJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 255493   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Rigel Pharmceuticals

US Patent
LigandPNGBDBM255493(US10828301, Compound R940269 | US9499493, R940269)
Affinity DataIC50:  685nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Rigel Pharmceuticals

US Patent
LigandPNGBDBM255493(US10828301, Compound R940269 | US9499493, R940269)
Affinity DataIC50:  685nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent