BDBM255740 US9475815, WO 2007/61737: 5::US9598416, Example 5 W 2007/061737
SMILES Cc1ccc2[nH]c(cc2c1)-c1nc(C2CCC2)n2ccnc(N)c12
InChI Key InChIKey=PJEKXBMIYGCRBL-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 255740
TargetFibroblast growth factor receptor 1 [400-80]/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intelletual Property
US Patent
Bayer Intelletual Property
US Patent
Affinity DataIC50: 500nMpH: 7.0 T: 2°CAssay Description:A recombinant tagged FGFR-1 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...More data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 3 [397-806]/Glutathione S-transferase P(Homo sapiens (Human))
Bayer Intelletual Property
US Patent
Bayer Intelletual Property
US Patent
Affinity DataIC50: 250nMpH: 7.0 T: 2°CAssay Description:A recombinant tagged FGFR-3 fusion protein [fusion of glutathione-S-transferase (GST) (N-terminally), His6-tag, thrombin cleavage site, and the intra...More data for this Ligand-Target Pair