BDBM25770 5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol::5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-diol, 5::Brethaire::Brethine::Bricanyl::Terbutaline::Terbutaline,(+/-)

SMILES CC(C)(C)NCC(O)c1cc(O)cc(O)c1

InChI Key InChIKey=XWTYSIMOBUGWOL-UHFFFAOYSA-N

Data  6 KI  5 IC50  10 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 25770   

TargetBeta-2 adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  3.98E+3nMAssay Description:Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  1.86E+3nMAssay Description:Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Institute of Cell Signaling

Curated by PDSP Ki Database
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  2.51E+3nMAssay Description:Binding affinity to beta-2 adrenergic receptor (unknown origin) at 1 to 10000 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Institute of Cell Signaling

Curated by PDSP Ki Database
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  2.51E+3nMAssay Description:Binding affinity to human adrenergic beta2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-2 adrenergic receptor(BOVINE)
TBA

Curated by ChEMBL
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  4.48E+3nMAssay Description:Apparent binding affinity constant to beta-2 adrenergic receptor determined using [3H]DHAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-adrenergic receptor kinase 1(Homo sapiens (Human))
Merck Sharp and Dohme Research Laboratories

LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  7.40E+3nMAssay Description:The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP Ki Database
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  1.26E+5nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Institute of Cell Signaling

Curated by PDSP Ki Database
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  3.20nMAssay Description:Displacement of [3H]-CGP12,177 from immobilized Halo tag-fused beta2 adrenoceptor (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
UniversitÄT WÜRzburg

Curated by PDSP Ki Database
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  1.51E+5nMpH: 7.4 T: 2°CAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Institute of Cell Signaling

Curated by PDSP Ki Database
LigandPNGBDBM25770(5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...)
Affinity DataKd:  2.40E+3nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank