BDBM258048 US9493446, 517

SMILES Cc1ccc(C(=O)N2CCC[C@H]2c2ncc([nH]2)-c2ccccc2OC(F)(F)F)c(c1)-n1nccn1

InChI Key InChIKey=ZFBTXWPCJCOJHZ-IBGZPJMESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 258048   

TargetOrexin receptor type 2(Homo sapiens (Human))
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM258048(US9493446, 517)
Affinity DataIC50:  2nMT: 2°CAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Actelion Pharmaceuticals

US Patent
LigandPNGBDBM258048(US9493446, 517)
Affinity DataIC50:  6nMT: 2°CAssay Description:Human orexin-A as an agonist is prepared as 1 mM stock solution in MeOH: water (1:1), diluted in HBSS containing 0.1% bovine serum albumin (BSA), NaH...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent