BDBM25836 3-[2-(3-hydroxyphenyl)-1,3-thiazol-4-yl]phenol::hydroxyphenyl substituted thiazole, 8

SMILES Oc1cccc(c1)-c1csc(n1)-c1cccc(O)c1

InChI Key InChIKey=WSUUHCNQLBCNOV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25836   

Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Saarland University

LigandPNGBDBM25836(3-[2-(3-hydroxyphenyl)-1,3-thiazol-4-yl]phenol | h...)
Affinity DataIC50:  2.22E+3nMAssay Description:Tritiated E2 was incubated with 17beta-HSD2, cofactor, and inhibitor. The amount of labeled E1 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Homo sapiens (Human))
Saarland University

LigandPNGBDBM25836(3-[2-(3-hydroxyphenyl)-1,3-thiazol-4-yl]phenol | h...)
Affinity DataIC50:  455nMpH: 7.0 T: 2°CAssay Description:Tritiated E1 was incubated with 17beta-HSD1, cofactor, and inhibitor. The amount of labeled E2 formed was quantified by HPLC. Detection and quantific...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed