BDBM258497 US10633384, Example 1.19::US9493486, 1.19
SMILES Clc1cc(Cl)cc(COC(=O)N2CCC3(C2)CCN(CC3)C(=O)c2ccc3[nH]nnc3c2)c1
InChI Key InChIKey=VKGKTWSBQKAVNC-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 258497
Affinity DataIC50: 39.5nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche
US Patent
Hoffmann-La Roche
US Patent
Affinity DataIC50: 39.5nMpH: 8.0 T: 2°CAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair