BDBM258509 US10633384, Example 2.2::US9493486, 2.2

SMILES Clc1cc(Cl)cc(COC(=O)N2CC3(C2)CCN(CC3)C(=O)c2ccc3[nH]c(=O)oc3c2)c1

InChI Key InChIKey=SIBYCEPFLIGWEY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 258509   

TargetAtaxin-2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM258509(US10633384, Example 2.2 | US9493486, 2.2)
Affinity DataIC50:  13.7nMAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM258509(US10633384, Example 2.2 | US9493486, 2.2)
Affinity DataIC50:  13.7nMpH: 8.0 T: 2°CAssay Description:ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent