BDBM259453 US9512114, 16::US9657007, Example 16

SMILES C[C@H](Nc1ncnc(N)c1-c1ncn(C)n1)c1cc2cccc(Cl)c2c(=O)n1C1CC1

InChI Key InChIKey=KGMUVLHTFOIEPG-NSHDSACASA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 259453   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Calitor Sciences

US Patent
LigandPNGBDBM259453(US9512114, 16 | US9657007, Example 16)
Affinity DataIC50:  190nMAssay Description:Kinase assays can be performed by measurement of incorporation of γ-33P ATP into immobilized myelin basic protein (MBP). High binding white 384 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM259453(US9512114, 16 | US9657007, Example 16)
Affinity DataIC50:  190nMT: 2°CAssay Description:PI3K (p110δ/p85α) (h) is incubated in assay buffer containing 10 μM phosphatidylinositol-4, 5-bisphosphate and MgATP (concentration as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent