BDBM261643 N-(4-(3-(hex-1-yn-1-yl)phenyl)thiazol-2-yl)-4-((4-methylpiperazin-1-yl)methyl)benzamide::US9708279, 20

SMILES CCCCC#Cc1cccc(c1)-c1csc(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)n1

InChI Key InChIKey=ULXXIWQPWWBLQD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261643   

TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
UniversitÁ

US Patent
LigandPNGBDBM261643(N-(4-(3-(hex-1-yn-1-yl)phenyl)thiazol-2-yl)-4-((4-...)
Affinity DataIC50:  3.10E+4nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
UniversitÁ

US Patent
LigandPNGBDBM261643(N-(4-(3-(hex-1-yn-1-yl)phenyl)thiazol-2-yl)-4-((4-...)
Affinity DataIC50:  3.80E+4nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent