BDBM261662 N-(4-(3-((3,5-bis(trifluoromethyl)phenyl)ethynyl)phenyl)thiazol-2-yl)-4-(morpholinomethyl)benzamide::US9708279, 39

SMILES FC(F)(F)c1cc(cc(c1)C(F)(F)F)C#Cc1cccc(c1)-c1csc(NC(=O)c2ccc(CN3CCOCC3)cc2)n1

InChI Key InChIKey=WMVPGEPORBGQPJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261662   

TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
UniversitÁ

US Patent
LigandPNGBDBM261662(N-(4-(3-((3,5-bis(trifluoromethyl)phenyl)ethynyl)p...)
Affinity DataIC50:  2.70E+4nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
UniversitÁ

US Patent
LigandPNGBDBM261662(N-(4-(3-((3,5-bis(trifluoromethyl)phenyl)ethynyl)p...)
Affinity DataIC50: >1.00E+5nMpH: 7.5 T: 2°CAssay Description:GST-tagged recombinant wild-type or L1196M mutated ALK kinase (rALK) was expressed in Sf9 insect cells using the pBacPAK baculovirus vector system (C...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent