BDBM261989 3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- dimethyl-1H-pyrazol-4-yl)-1- (pyridazin-3-ylmethyl)-3,4- dihydropyrido[4,3-d]pyrimidin- 2(1H)-one::US10251892, Example 88::US10632126, Example 88::US11173162, Example 88::US9708318, 88

SMILES COc1cc(OC)c(F)c(N2Cc3cnc(cc3N(Cc3cccnn3)C2=O)-c2cn(C)nc2C)c1F

InChI Key InChIKey=FUABQJSONSLJEA-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 261989   

TargetFibroblast growth factor receptor 4(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM261989(3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- dime...)
Affinity DataIC50: <10nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM261989(3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- dime...)
Affinity DataIC50: <10nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 2(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM261989(3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- dime...)
Affinity DataIC50: <10nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFibroblast growth factor receptor 3(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM261989(3-(2,6-difluoro-3,5- dimethoxyphenyl)-7-(1,3- dime...)
Affinity DataIC50: <10nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent