BDBM26280 2-{3-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propoxy}-6-methoxyquinazolin-4-yl)amino]-1H-pyrazol-5-yl}-N-(3-nitrophenyl)acetamide::pyrazoloquinazoline deriv., 14
SMILES COc1cc2c(Nc3cc(CC(=O)Nc4cccc(c4)[N+]([O-])=O)n[nH]3)ncnc2cc1OCCCN1CCC(CO)CC1
InChI Key InChIKey=PJXJTLKNCJRPQT-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 26280
Affinity DataKi: 39nM ΔG°: -10.0kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 890nM ΔG°: -8.25kcal/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair