BDBM26283 2-{3-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propoxy}-6-methoxyquinazolin-4-yl)amino]-1H-pyrazol-5-yl}-N-[3-(trifluoromethyl)phenyl]acetamide::pyrazoloquinazoline deriv., 17
SMILES COc1cc2c(Nc3cc(CC(=O)Nc4cccc(c4)C(F)(F)F)n[nH]3)ncnc2cc1OCCCN1CCC(CO)CC1
InChI Key InChIKey=CSIWGLJKPPOVQR-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 26283
Affinity DataKi: 13nM ΔG°: -10.6kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
Affinity DataKi: 510nM ΔG°: -8.58kcal/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair