BDBM26394 2,4-diamino-5,6-disubstituted pyrimidine, 8::4-(piperazin-1-yl)-5H-indeno[1,2-d]pyrimidin-2-amine

SMILES Nc1nc-2c(Cc3ccccc-23)c(n1)N1CCNCC1

InChI Key InChIKey=UXPDQPNIBOHOSD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26394   

TargetHistamine H4 receptor(Rattus norvegicus (rat))
Abbott Laboratories

LigandPNGBDBM26394(2,4-diamino-5,6-disubstituted pyrimidine, 8 | 4-(p...)
Affinity DataKi:  4.80nM ΔG°:  -11.3kcal/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM26394(2,4-diamino-5,6-disubstituted pyrimidine, 8 | 4-(p...)
Affinity DataKi:  13nM ΔG°:  -10.8kcal/molepH: 7.4 T: 2°CAssay Description:Competition radioligand binding assays were performed with increasing concentrations of test compound in the presence of [3H]ligand. All binding reac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed