BDBM26533 (1S,3R)-6-{3-fluoro-4-[(2-phenylquinolin-4-yl)methoxy]phenyl}-N-hydroxy-5-methyl-4-oxo-5-azaspiro[2.4]heptane-1-carboxamide::hydroxamate-spirocyclopropyl compound, 18

SMILES CN1C(C[C@@]2(C[C@@H]2C(=O)NO)C1=O)c1ccc(OCc2cc(nc3ccccc23)-c2ccccc2)c(F)c1

InChI Key InChIKey=NIMFDLGXDWOYBK-YDSPQXFFSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26533   

TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM26533((1S,3R)-6-{3-fluoro-4-[(2-phenylquinolin-4-yl)meth...)
Affinity DataKi:  137nM ΔG°:  -9.26kcal/molepH: 7.3 T: 2°CAssay Description:Enzyme activity was determined by a kinetic assay measuring the rate of increase in fluorescent intensity generated by the cleavage of an internally ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed