BDBM26608 3-(3,4-dimethylphenoxymethyl)furan-2-carboxylic acid::cid_580604::furan carboxylic acid analogue, 33

SMILES Cc1ccc(OCc2ccoc2C(O)=O)cc1C

InChI Key InChIKey=JWVMSZBUUVSMRB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26608   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Southern California

LigandPNGBDBM26608(3-(3,4-dimethylphenoxymethyl)furan-2-carboxylic ac...)
Affinity DataIC50:  1.10E+4nMAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor beta(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM26608(3-(3,4-dimethylphenoxymethyl)furan-2-carboxylic ac...)
Affinity DataIC50:  5.86E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEstrogen receptor beta(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM26608(3-(3,4-dimethylphenoxymethyl)furan-2-carboxylic ac...)
Affinity DataIC50:  23nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEstrogen receptor(Homo sapiens (Human))
Emory University

Curated by PubChem BioAssay
LigandPNGBDBM26608(3-(3,4-dimethylphenoxymethyl)furan-2-carboxylic ac...)
Affinity DataIC50:  2.54E+4nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: John A. Katzenellenbogen, ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay