BDBM26627 (5Z)-3-{[4-(trifluoromethoxy)phenyl]methyl}-5-{[3-(trifluoromethyl)phenyl]methylidene}-1,3-thiazolidine-2,4-dione::thiazolidine-2,4-dione, 5a

SMILES FC(F)(F)Oc1ccc(CN2C(=O)S\C(=C/c3cccc(c3)C(F)(F)F)C2=O)cc1

InChI Key InChIKey=IZDAXLSKLAFJRU-DHDCSXOGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26627   

TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Medical University of South Carolina

LigandPNGBDBM26627((5Z)-3-{[4-(trifluoromethoxy)phenyl]methyl}-5-{[3-...)
Affinity DataIC50: >1.00E+5nMAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Medical University of South Carolina

LigandPNGBDBM26627((5Z)-3-{[4-(trifluoromethoxy)phenyl]methyl}-5-{[3-...)
Affinity DataIC50:  2.80E+4nMpH: 7.0 T: 2°CAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed