BDBM26663 (2S)-5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one::(S)-5,7-dihydroxy-8-(3-methylbut-2-ene)flavanone

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])cc(-[#8])c2-[#6](=O)-[#6]-[#6@H](-[#8]-c12)-c1ccccc1

InChI Key InChIKey=DAWSYIQAGQMLFS-SFHVURJKSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26663   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Loma Linda University

LigandPNGBDBM26663((2S)-5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-2-phe...)
Affinity DataIC50:  1.25E+4nMpH: 7.0 T: 2°CAssay Description:The 96-well flat-bottomed plates were coated with recombinant GST-BAD. After the plates were blocked, the reaction buffer containing test compound an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Ciudad Universitaria

Curated by ChEMBL
LigandPNGBDBM26663((2S)-5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-2-phe...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate measured after 30 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
TBA

Curated by ChEMBL
LigandPNGBDBM26663((2S)-5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-2-phe...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of Electrophorus electricus C2888 AChE using acetylthiocholine iodide as substrate by Ellman's spectroscopic methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Loma Linda University

LigandPNGBDBM26663((2S)-5,7-dihydroxy-8-(3-methylbut-2-en-1-yl)-2-phe...)
Affinity DataIC50:  1.26E+4nMAssay Description:Inhibition of PIM1 kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed