BDBM269347 (R)-1-((1-(1-hydroxycyclopropanecarbonyl)pyrrolidin-3-yl)methyl)-4,4-dimethyl-2-(2-methyl-4-(1-methyl-1H-benzo[d]imidazol-5-yl)phenyl)-1H-imidazol-5(4H)-one ::US10413545, Compound 92::US9718813, Compound 92
SMILES Cc1cc(ccc1C1=NC(C)(C)C(=O)N1C[C@@H]1CCN(C1)C(=O)C1(O)CC1)-c1ccc2n(C)cnc2c1
InChI Key InChIKey=KDGDSGHLTUVPGB-LJQANCHMSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 269347
Affinity DataIC50: 91.2nMAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair
Affinity DataIC50: 91.2nMpH: 7.5 T: 2°CAssay Description:In this assay, inhibition of FASN activity is measured using 3H-acetyl-CoA and malonyl-CoA as substrates. 3H-Acetyl CoA is converted to 3H-palmitate ...More data for this Ligand-Target Pair