BDBM26942 8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)-3-{2-[(2-methylpropyl)amino]ethyl}-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::spiropiperidine analogue, 63

SMILES CC(C)CNCCN1CN(c2ccccc2)C2(CCN(CC2)C2CCC(C)(C)c3ccccc23)C1=O

InChI Key InChIKey=MTJGMTDHBHXMOS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26942   

TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM26942(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  0.5nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM26942(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  61nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM26942(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  65nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

LigandPNGBDBM26942(8-(4,4-dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)...)
Affinity DataKi:  1.80E+3nMAssay Description:IC50 values were obtained by fitting the competition binding curves according to a 4-parameter logistic model. Inhibition constants Ki were derived f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed