BDBM269446 (E)-3-(4-((7-fluoro-6- hydroxy-2-(2- isopropylphenyl)benzo [b]thiophen-3- yl)oxy)phenyl)acrylic acid::US10058534, 101

SMILES CC(C)c1ccccc1-c1sc2c(F)c(O)ccc2c1Oc1ccc(\C=C\C(O)=O)cc1

InChI Key InChIKey=QSKXCBRVAMHJPL-NTEUORMPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 269446   

TargetEstrogen receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM269446((E)-3-(4-((7-fluoro-6- hydroxy-2-(2- isopropylphen...)
Affinity DataIC50:  0.200nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM269446((E)-3-(4-((7-fluoro-6- hydroxy-2-(2- isopropylphen...)
Affinity DataIC50:  4.20nMpH: 5.1 T: 2°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent