BDBM269743 (2S,3R)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide::US10058550, Example 263.0

SMILES COc1cccc(OC)c1\N=C(/CS(=O)(=O)[C@@H](C)[C@H](C)c1ncc(C)cn1)NNC(=O)c1cncc(C)c1

InChI Key InChIKey=BIGOJFZITUPCQS-OALUTQOASA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 269743   

TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269743((2S,3R)—N-(4-(2,6-dimethoxyphenyl)-5-(5-methy...)
Affinity DataEC50:  0.320nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent