BDBM270116 (2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-pyridinyl)-4H-1,2,4-triazol-3-yl)-3-(5-methoxy-2-pyrimidinyl)-2-butanesulfonamide::US10058550, Example 682.0::US10221162, Example 682.0::US9845310, Example 682.0

SMILES COc1cnc(nc1)[C@@H](C)[C@H](C)S(=O)(=O)Nc1nnc(-c2cncc(C)c2)n1-c1c(OC)cccc1OC

InChI Key InChIKey=ANLMXEHFURHGBW-IRXDYDNUSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 270116   

TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM270116((2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-p...)
Affinity DataEC50:  0.200nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM270116((2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-p...)
Affinity DataEC50:  0.200nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM270116((2S,3R)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methyl-3-p...)
Affinity DataEC50:  0.200nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent