BDBM27166 1H-indol-1-yl tertiary amine, 10::{[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)[3-(1H-indazol-3-yloxy)propyl]amine

SMILES FC(F)(F)c1cccc(CN(CCCOc2n[nH]c3ccccc23)CC(c2ccccc2)c2ccccc2)c1Cl

InChI Key InChIKey=JFYYICQUPIPHLA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27166   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
Gsk

LigandPNGBDBM27166(1H-indol-1-yl tertiary amine, 10 | {[2-chloro-3-(t...)
Affinity DataEC50:  60nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
Gsk

LigandPNGBDBM27166(1H-indol-1-yl tertiary amine, 10 | {[2-chloro-3-(t...)
Affinity DataEC50:  110nMpH: 7.5 T: 2°CAssay Description:The LXR LiSA measures the ligand-dependent recruitment of a 25 amino acid fragment of the steroid receptor coactivator 1 (SRC1) to the ligand-binding...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed