BDBM272555 US10065967, Example 21::US10759805, Ex 21::US9745307, Example 21

SMILES Cc1cccc(CN2Cc3cc4c(n[nH]c4cc3NC2=O)-c2ccnc(C)c2)n1

InChI Key InChIKey=OUOZZVSWSXPESX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 272555   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM272555(US10065967, Example 21 | US10759805, Ex 21 | US974...)
Affinity DataIC50:  0.600nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM272555(US10065967, Example 21 | US10759805, Ex 21 | US974...)
Affinity DataIC50:  600nMAssay Description:Human: Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM272555(US10065967, Example 21 | US10759805, Ex 21 | US974...)
Affinity DataIC50:  0.600nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent