BDBM273199 (R)-N-benzyl-1-[2-(2-fluorophenyl)-4-oxo-3,4-dihydropyrido[3,2-d]pyrimidin-6-yl]pyrrolidine-2-carboxamide::US10065972, Example 713
SMILES Fc1ccccc1-c1nc2ccc(nc2c(=O)[nH]1)N1CCC[C@@H]1C(=O)NCc1ccccc1
InChI Key InChIKey=CPQWGDHWJASSIA-HXUWFJFHSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 273199
TargetKynurenine/alpha-aminoadipate aminotransferase, mitochondrial(Homo sapiens (Human))
Mitsubishi Tanabe Pharma
US Patent
Mitsubishi Tanabe Pharma
US Patent
Affinity DataIC50: 88nMpH: 8.0Assay Description:The inhibitory action of the test compound on human recombinant KAT-II was determined by the following method.To a reaction mixture (45 μL) cont...More data for this Ligand-Target Pair