BDBM273221 5-Amino-3-[(2R,3S,5S)-5-[(1S)-1-hydroxypropyl]-3-[(1S)-1-methoxyethyl]tetrahydrofuran-2-yl]-6H-thiazolo[4,5-d]pyrimidine-2,7-dione::US10065973, Example 16

SMILES [H][C@]1(C[C@@]([H])([C@H](C)OC)[C@@H](O1)n1c2nc(N)[nH]c(=O)c2sc1=O)[C@@H](O)CC

InChI Key InChIKey=QASRLHHBDRZLTA-HQDUHMNQSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273221   

TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM273221(5-Amino-3-[(2R,3S,5S)-5-[(1S)-1-hydroxypropyl]-3-[...)
Affinity DataEC50:  3.50E+4nMAssay Description:HEK293-Blue-hTLR7 cells were incubated at a density of 250,000-450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Modif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent