BDBM274858 N-(6-(4-(4-Fluorophenyl)- 1-(tetrahydro-2H- pyran-4-yl)-1H-imidazol- 5-yl)imidazo[1,2- b]pyridazin-2-yl)-3- (pyridin-3-yl)benzamide::US9556179, Compound 435

SMILES Fc1ccc(cc1)-c1ncn(C2CCOCC2)c1-c1ccc2nc(NC(=O)c3cccc(c3)-c3cccnc3)cn2n1

InChI Key InChIKey=UZEMKIULWVKKBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 274858   

TargetCasein kinase I isoform delta(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM274858(N-(6-(4-(4-Fluorophenyl)- 1-(tetrahydro-2H- pyran-...)
Affinity DataIC50:  0.200nMpH: 7.4 T: 2°CAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM274858(N-(6-(4-(4-Fluorophenyl)- 1-(tetrahydro-2H- pyran-...)
Affinity DataIC50:  1.40nMpH: 7.4 T: 2°CAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent