BDBM274896 Methyl 3-(2-(2-fluoroisonicotinamido)imidazo[1,2-b]pyridazin-6-yl)-2-(4-fluorophenyl)-5,6-dihydroimidazo[1,2-a]pyrazine-7(8H)-carboxylate::US9556179, Compound 474

SMILES COC(=O)N1CCn2c(C1)nc(c2-c1ccc2nc(NC(=O)c3ccnc(F)c3)cn2n1)-c1ccc(F)cc1

InChI Key InChIKey=PZUJMBRTVSRHLX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 274896   

TargetCasein kinase I isoform delta(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM274896(Methyl 3-(2-(2-fluoroisonicotinamido)imidazo[1,2-b...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM274896(Methyl 3-(2-(2-fluoroisonicotinamido)imidazo[1,2-b...)
Affinity DataIC50:  9.30nMpH: 7.4 T: 2°CAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent