BDBM275426 1-[7-(hydroxymethyl)-1-propyl- 1H-pyrazolo[3,4-c]pyridin-5-yl]-3- [(1R)-1-phenylethyl]urea::US9884048, Example 305

SMILES CCCn1ncc2cc(NC(=O)N[C@H](C)c3ccccc3)nc(CO)c12

InChI Key InChIKey=NFHZBFNDLHFDTO-CYBMUJFWSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275426   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM275426(1-[7-(hydroxymethyl)-1-propyl- 1H-pyrazolo[3,4-c]p...)
Affinity DataIC50:  44nMAssay Description:Activated ERK2 activity was determined in an IMAP-FP assay (Molecular Devices). Using this assay format, the potency (IC50) of each compound was dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent