BDBM275463 US9879013, 8

SMILES Nc1ncnc2n(C3CN(C3)C(=O)C=C)c(=O)n(-c3ccc(Oc4ccccc4)cc3)c12

InChI Key InChIKey=JDJIUBQAXIUQGA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 275463   

TargetTyrosine-protein kinase BTK/Lck(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM275463(US9879013, 8)
Affinity DataIC50:  8.00E+4nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Lyn(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM275463(US9879013, 8)
Affinity DataIC50:  4.59E+5nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Fyn(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM275463(US9879013, 8)
Affinity DataIC50:  4.53E+5nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent