BDBM275784 5-chloro-4-((5-chloro- 6-isobutoxypyridin- 3-yl)oxy)-N-(N,N- dimethylsulfamoyl)- 2-fluorobenzamide::US10071957, Example 3
SMILES CC(C)COc1ncc(Oc2cc(F)c(cc2Cl)C(=O)NS(=O)(=O)N(C)C)cc1Cl
InChI Key InChIKey=FPPKSWZDWMUMIR-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 275784
Affinity DataIC50: 11nMpH: 7.2Assay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair
Affinity DataIC50: 24.8nMpH: 7.4 T: 2°CAssay Description:Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...More data for this Ligand-Target Pair
Affinity DataIC50: 2.18E+3nMpH: 7.2Assay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair