BDBM275809 N-((1H-imidazol-4- yl)sulfonyl)-5-chloro- 4-((5-chloro-6- isobutoxypyridin- 3-yl)oxy)-2- fluorobenzamide::US10071957, Example 26
SMILES CC(C)COc1ncc(Oc2cc(F)c(cc2Cl)C(=O)NS(=O)(=O)c2c[nH]cn2)cc1Cl
InChI Key InChIKey=SYKGVYUTMUAYJI-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 275809
Affinity DataIC50: 77.3nMpH: 7.4 T: 2°CAssay Description:Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMpH: 7.2Assay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair