BDBM275812 US10071957, Example 29::tert-butyl N-(5-chloro-4-((5- chloro-6-isobutoxy- pyridin-3-yl)oxy)- 2-fluorobenzoyl) sulfamoylcarbamate

SMILES CC(C)COc1ncc(Oc2cc(F)c(cc2Cl)C(=O)NS(=O)(=O)NC(=O)OC(C)(C)C)cc1Cl

InChI Key InChIKey=DYAPPWFTVGRFPT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 275812   

TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM275812(US10071957, Example 29 | tert-butyl N-(5-chloro-4-...)
Affinity DataIC50:  905nMpH: 7.4 T: 2°CAssay Description:Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent