BDBM275821 5-chloro-4-(((5-chloro- 6-(2,2,3,3-tetrafluoro- propoxy)pyridin- 3-yl)oxy)methyl)- N-(N,N-dimethyl- sulfamoyl)-2-fluoro- benzamide::US10071957, Example 39::US10071957, Example 76
SMILES CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(COc2cnc(OCC(F)(F)C(F)F)c(Cl)c2)cc1F
InChI Key InChIKey=JWJGDFKYGVLSIF-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 275821
Affinity DataIC50: 216nMpH: 7.4 T: 2°CAssay Description:Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...More data for this Ligand-Target Pair
Affinity DataIC50: 220nMpH: 7.4 T: 2°CAssay Description:Preparation of membranes containing recombinantly expressed sodium channels: Frozen recombinant cell pellets were thawed on ice and diluted to 4 time...More data for this Ligand-Target Pair
Affinity DataIC50: 34.3nMpH: 7.2Assay Description:Patch voltage clamp electrophysiology allows for the direct measurement and quantification of block of voltage-gated sodium channels (NaV's), and...More data for this Ligand-Target Pair