BDBM276124 2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4-yl]methoxy]-5-::US10071988, Example 154::US10071988, Example 31::US10233173, Example 31

SMILES Cc1cnc(OCc2cn(nn2)-c2ccc(Cl)c(c2)C(F)F)nc1

InChI Key InChIKey=YILFBGPEHUAPIV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 276124   

TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276124(2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4...)
Affinity DataIC50:  1nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276124(2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4...)
Affinity DataIC50:  1nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRetinoic acid receptor RXR-alpha(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM276124(2-[[1-[4-Chloro-3-(difluoromethyl)phenyl]triazol-4...)
Affinity DataIC50:  30nMpH: 7.4 T: 2°CAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent