BDBM278729 N-(3-chloro-1-methyl- 1H-pyrazol-4-yl)-2- (2,5- diazabicyclo[2.2.2]oct- 2-yl)pyrrolo[1,2- b]pyridazine-7- carboxamide trifluoroacetate::US10040798, Example 26
SMILES OC(=O)C(F)(F)F.Cn1cc(NC(=O)c2ccc3ccc(nn23)N2CC3CCC2CN3)c(Cl)n1
InChI Key InChIKey=NOPBJFFLCKEKFV-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 278729
Affinity DataIC50: 28nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair