BDBM278752 2-[(1S,5S)- or (1R,5R)- 3,6- diazabicyclo[3.2.1]oct- 3-yl]-N-[3- (difluoromethyl)-1- methyl-1H-pyrazol-4- yl]pyrrolo[1,2- b]pyridazine-7- carboxamide::US10040798, Example 50::US10040798, Example 51
SMILES Cn1cc(NC(=O)c2ccc3ccc(nn23)N2C[C@@H]3C[C@H](C2)N3)c(n1)C(F)F
InChI Key InChIKey=BVBUDXSHAUSZPV-PHIMTYICSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 278752
Affinity DataIC50: 12nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair