BDBM283124 (R)-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)methyl methanesulfonate ::US9884874, Compound 15

SMILES Cc1sc(NC(=O)[C@@H]2COC(C)(C)N2C(=O)OC(C)(C)C)c(C(=O)c2ccc(Cl)cc2)c1C

InChI Key InChIKey=LOTPQGYZXJJTKW-KRWDZBQOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 283124   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Kainos Medicine

US Patent
LigandPNGBDBM283124((R)-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[...)
Affinity DataIC50:  100nMAssay Description:Bromodomain binding assays were carried out in Reaction Biology (PA, USA) to test the degrees of the inventive compounds in inhibiting the human BRD4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent