BDBM283264 2-fluoro-4-[5-(3-fluoro- 4-methoxy-phenyl)-1-methyl-6- oxo-2-piperazin-1-yl-1,6-dihydro- pyrimidin-4-yl]-benzonitrile::US10023543, Example 47::US10207999, Example 47::US10328077, Example 47::US10548896, Example 47::US10849898, Example 47::US10960005, Example 47::US11084793, Example 47::US9573930, Example 47::US9771329, Example 47::US9776974, Example 47
SMILES COc1ccc(cc1F)-c1c(nc(N2CCNCC2)n(C)c1=O)-c1ccc(C#N)c(F)c1
InChI Key InChIKey=IOLJIBCUDFSHTI-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 283264
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair