BDBM283296 4-[2-(4-amino-piperidin-1-yl)-5- (1H-indazol-6-yl)-1-methyl-6-oxo- 1,6-dihydro-pyrimidin-4-yl]- 2-fluoro-benzonitrile::US10023543, Example 77::US10207999, Example 77::US10328077, Example 77::US10548896, Example 77::US10849898, Example 77::US10960005, Example 77::US11084793, Example 77::US9573930, Example 77::US9771329, Example 77::US9776974, Example 77
SMILES Cn1c(nc(-c2ccc(C#N)c(F)c2)c(-c2ccc3cn[nH]c3c2)c1=O)N1CCC(N)CC1
InChI Key InChIKey=OWFYKUAMNLBJNG-UHFFFAOYSA-N
Data 12 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 283296
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Celgene Quanticel Research
US Patent
Celgene Quanticel Research
US Patent
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of LSD-1 activity is based on Tnne Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties...More data for this Ligand-Target Pair