BDBM283407 3-chloro-6-((4-(((3-chloro-6-fluoro-1H-indol-5- yl)methyl)carbamoyl)pyridin-2- yl)methyl)quinoline-8-carboxamide::US10023557, Example 59::US10266515, Example 59::US11021463, Example 59::US9611252, Example 59

SMILES NC(=O)c1cc(Cc2cc(ccn2)C(=O)NCc2cc3c(Cl)c[nH]c3cc2F)cc2cc(Cl)cnc12

InChI Key InChIKey=QMNRPOHMXWHKMB-UHFFFAOYSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 283407   

TargetPlasma kallikrein(Homo sapiens (Human))
Lifesci Pharmaceuticals

US Patent
LigandPNGBDBM283407(3-chloro-6-((4-(((3-chloro-6-fluoro-1H-indol-5- yl...)
Affinity DataIC50: <100nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent